Abstract:The single factor + Box-Behnken response surface method was used to optimize the impurity removal process of ammonium tungstate solution evaporation crystallization method to prepare higher purity ammonium paratungstate (APT). Firstly, in order to reduce the total content of four impurities (Na, K, S, Mo elements) in APT, the preferred range of crystallization temperature, stirring speed and initial concentration of ammonium tungstate solution was preliminarily determined by single factor method. Secondly, the evaporation crystallization impurity removal process of APT was further optimized by Box-Behnken response surface method, and the mutual influence of three factors on the total amount of four impurities in APT was studied. The results show that the order of influence of three factors on the total amount of four impurities is : initial concentration of ammonium tungstate solution > evaporation temperature > stirring speed ; the optimum process conditions were as follows : evaporation temperature 94 °C, stirring speed 1.25 m/s, initial concentration of ammonium tungstate solution 73 g/L. Under the experimental conditions, the total content of the four impurities in the prepared APT was reduced to 39.351 ppm, and the relative error with the optimal prediction value of the response surface method model was only 4.110 %, and the purity of APT reached 4N. The generated APT crystal is a columnar cuboid morphology with a small amount of broken crystals. The layered structure is obvious, the particle size distribution is uniform, and the grain refinement is obvious.