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激光加工鎂合金表面形貌的生物相容性
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1.濟南大學 機械工程學院，山東 濟南 250022;2.山東省青島市市北區(qū)教育和體育局，山東 青島 266022;3.山東大學第二醫(yī)院 基礎醫(yī)學研究所，山東 濟南 250033;4.山東大學第二醫(yī)院 創(chuàng)傷骨科，山東 濟南 250031

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基金項目:

山東省自然科學基金項目(ZR2023ME077, ZR2023MC140)，國家自然科學基金項目(批準號52175408)。


Biocompatibility of Morphology on Laser-Processed Magnesium Alloy Surfaces
Author:
Affiliation:

1.School of Mechanical Engineering, University of Jinan, Jinan250022, China;2.Shibei District of Education and Sports Bureau, Qingdao of Shandong Province, Qingdao266022, China;3.Institute of Basic Medical Sciences, The Second Hospital of Shandong University, Jinan250033, China;4.Traumatic & Orthopedics Department, The Second Hospital of Shandong University, Jinan250031, China

Fund Project:

Shandong Provincial Natural Science Foundation (ZR2023ME077, ZR2023MC140); National Natural Science Foundation of China (52175408)

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    摘要:

    對鎂合金表面進行激光加工改性，通過觀察羊肋骨表面形貌，確定激光刻蝕形貌為溝槽。通過接觸角測試，探究鎂合金表面不同形貌的潤濕性。通過細胞粘附試驗，探究不同形貌的鎂合金表面對細胞粘附、生長、遷移的影響。結果表明，田形形貌潤濕角比溝槽形貌小，田形形貌的鎂合金表面有更好的親水性；與光滑表面相比，田形表面細胞附著性好，凹陷及凸起處均鋪滿細胞，這說明經(jīng)過激光加工處理獲得的顯微圖案有利于生物相容性的提高。

    Abstract:

    The surface of magnesium alloy was laser-processed, and the laser-etched morphology was determined as grooves by observing the surface morphology of sheep rib bone. The wettability of different morphologies was investigated by contact angle test. Through the cell adhesion test, the effects of different morphologies on cell adhesion, growth and migration were investigated. Results show that the wetting angle of the block-shaped surface is smaller than that of the groove-shaped surface, and block-shaped surface has better hydrophilicity. Compared with the smooth surface, the block-shaped surface has better cell adhesion, and the depressions and bumps are full of cells, suggesting that the micropatterns prepared by the laser processing are conducive to the enhancement of biocompatibility.

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劉鵬,郭璇,高冬芳,趙洋洋,喬陽.激光加工鎂合金表面形貌的生物相容性[J].稀有金屬材料與工程,2024,53(12):3321~3328.[Liu Peng, Guo Xuan, Gao Dongfang, Zhao Yangyang, Qiao Yang. Biocompatibility of Morphology on Laser-Processed Magnesium Alloy Surfaces[J]. Rare Metal Materials and Engineering,2024,53(12):3321~3328.]
DOI：10.12442/j. issn.1002-185X.20240249

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  • 收稿日期:2024-04-28
  • 最后修改日期:2024-06-04
  • 錄用日期:2024-06-07
  • 在線發(fā)布日期: 2024-12-19
  • 出版日期: 2024-12-16