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醫(yī)用鎂合金表面改性改善耐蝕性研究進(jìn)展
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作者單位:

1.西安建筑科技大學(xué) 冶金工程學(xué)院,陜西 西安 710055;2.西北有色金屬研究院,陜西 西安 710016;3.西北有色金屬寶雞創(chuàng)新研究院,陜西 寶雞 721013;4.西北有色金屬研究院 陜西省醫(yī)用金屬材料重點(diǎn)實(shí)驗(yàn)室,陜西 西安 710016

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基金項(xiàng)目:

陜西省重點(diǎn)研發(fā)計(jì)劃項(xiàng)目 (2020ZDLGY13-05、2022SF-294、2023-YBSF-354)、西安市科技計(jì)劃項(xiàng)目(22GXFW0143)、未央?yún)^(qū)科技計(jì)劃項(xiàng)目(202106)、西北有色金屬研究院科技項(xiàng)目(YK2113、YK2119)


Advances in Medical Magnesium Alloy Surface Modification for Corrosion Resistance Improvement
Author:
Affiliation:

1.School of Metallurgical Engineering, Xi'an University of Architecture and Technology, Xi'an710055, China;2.Northwest Institute for Non-ferrous Metal Research, Xi'an710016, China;3.Northwest Nonferrous Metal Baoji Innovation Research Institute, Baoji721013, China;4.Shaanxi Key Laboratory of Biomedical Metal Materials, Northwest Institute for Nonferrous Metal Research, Xi 'an710016, China

Fund Project:

Key R&D Plan Projects in Shaanxi Province (2020ZDLGY13-05, 2022SF-294, 2023-YBSF-354); Xi'an City Research Science and Technology Project (22GXFW0143); Weiyang District Research Science and Technology Project (202106); Northwest Institute for Nonferrous Metal Research Science and Technology Project (YK2113, YK2119)

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    摘要:

    鎂及鎂合金具有優(yōu)異的生物安全性、獨(dú)特的生物可降解性和良好的載荷傳遞性等優(yōu)點(diǎn),在醫(yī)用植入領(lǐng)域應(yīng)用前景廣闊。良好的耐蝕性是鎂及鎂合金作為醫(yī)用植入物重要的前提條件之一。然而,鎂合金耐蝕性差,在生理環(huán)境中因過快腐蝕而迅速降解,導(dǎo)致其尚未完成服役就失去了固定支撐作用,嚴(yán)重限制了臨床應(yīng)用。對(duì)鎂合金進(jìn)行表面改性處理,改善其表面耐蝕性和生物相容性,已成為醫(yī)用鎂合金表面改性的研究熱點(diǎn)。圍繞改善醫(yī)用鎂合金表面耐蝕性研究進(jìn)展,介紹了醫(yī)用鎂合金的發(fā)展歷程及特點(diǎn),并從微弧氧化和離子注入等表面改性技術(shù)的原理,以及表面改性后鎂合金表面微觀結(jié)構(gòu)和性能等方面進(jìn)行綜述。討論了多種涂層的形成機(jī)制并分析其結(jié)構(gòu)和性能,闡述了涂層對(duì)鎂合金降解速率的影響規(guī)律,旨在明確醫(yī)用鎂合金表面改性在實(shí)施和應(yīng)用過程中存在的關(guān)鍵問題及可能的解決途徑,并就醫(yī)用鎂合金表面改性的發(fā)展方向提出了建議。

    Abstract:

    Since the magnesium and magnesium alloys have good load transmission, exceptional biosafety, unique biodegradability, etc, they have significant application possibilities in the field of medical implantation. Furthermore, excellent corrosion resistance is one of the paramount prerequisites for magnesium and magnesium alloys as medical implants. However, magnesium alloys exhibit poor corrosion resistance, leading to rapid degradation in physiological environments due to high corrosion rates. This premature degradation, before completing their intended service life, compromises their structural integrity, severely limiting their clinical applications. Surface modification treatment of magnesium alloy to improve corrosion resistance has become a research hotspot of medical magnesium alloy. This study primarily focused on the research advancements in the corrosion resistance enhancement of medical magnesium alloys. The developmental trajectory and characteristics of medical magnesium alloys were outlined. Additionally, surface modification techniques such as micro-arc oxidation and ion implantation, as well as microstructure and properties of magnesium alloy surfaces after surface modification were reviewed. The formation mechanisms of various coatings were discussed, and their structures and properties were analyzed. The impact of coatings on the degradation rate of magnesium alloys was elucidated, aiming to identify key issues and potential solutions in the implementation and application of surface modification for medical magnesium alloys. Recommendations were also provided, presenting the research directions for surface modification of medical magnesium alloys.

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趙晨,慕偉意,姬壽長,李歡,何飛,荊磊,徐伯文,梁李斯.醫(yī)用鎂合金表面改性改善耐蝕性研究進(jìn)展[J].稀有金屬材料與工程,2024,53(11):3084~3100.[Zhao Chen, Mu Weiyi, Ji Shouchang, Li Huan, He Fei, Jing Lei, Xu Bowen, Liang Lisi. Advances in Medical Magnesium Alloy Surface Modification for Corrosion Resistance Improvement[J]. Rare Metal Materials and Engineering,2024,53(11):3084~3100.]
DOI:10.12442/j. issn.1002-185X.20240063

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  • 收稿日期:2024-02-01
  • 最后修改日期:2024-09-13
  • 錄用日期:2024-05-23
  • 在線發(fā)布日期: 2024-11-18
  • 出版日期: 2024-11-08