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鎂合金表面可降解聚合物改性涂層研發(fā)及應(yīng)用
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暨南大學(xué) 先進(jìn)耐磨蝕及功能材料研究院

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國(guó)家重點(diǎn)研發(fā)計(jì)劃(項(xiàng)目號(hào)2020YFC1107202);陜西省重點(diǎn)研發(fā)計(jì)劃(項(xiàng)目號(hào)2019ZDLSF03-06)


Development and application of degradable polymer modified coating on magnesium alloy surface
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Institute of Advanced Wear Corrosion Resistant and Functional Materials,Ji Nan University

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    摘要:

    相比于鈦合金、不銹鋼、鈷基合金等傳統(tǒng)生物醫(yī)用金屬材料,鎂合金不僅具有生物可降解特性,而且其彈性模量與人體骨骼很接近,不容易產(chǎn)生“應(yīng)力屏蔽”,被譽(yù)為“新一代先進(jìn)生物材料”。但鎂合金在人體降解速率過快,由此產(chǎn)生的力學(xué)失穩(wěn)和過量降解產(chǎn)物在體內(nèi)的代謝吸收隱患限制了其在外科植介入醫(yī)療領(lǐng)域的大量推廣應(yīng)用。而可生物降解或可吸收的天然和合成高分子(聚合物)是全球量大面廣的一類質(zhì)輕、多功效、生物安全性好的生物醫(yī)用材料,若將其作為可降解鎂合金表面的特種防護(hù)涂層并解決好兩者表界面之間的生物功能性和力學(xué)相容性,將是開發(fā)先進(jìn)鎂合金材料及其應(yīng)用的重要發(fā)展方向。本文綜述了生物可降解的鎂基合金表面天然及合成高分子涂層的最新研究進(jìn)展,并對(duì)其未來的研發(fā)及應(yīng)用發(fā)展趨勢(shì)提出展望。

    Abstract:

    Compared with traditional biomedical metal materials, such as titanium alloys, stainless steels, cobalt-base alloys, magnesium alloys not only possess biodegradable properties, but also its elastic modulus is close to human bone, so it is hard to induce the effect of ing", so it is known as "new generation of advanced biomaterials". However, the degradation rate of magnesium alloy in human body is too fast, resulting in mechanical instability and metabolic absorption of excessive degradation products in vivo, which limits its application in the field of surgical implant and intervention. Biodegradable or absorbable natural and synthetic polymers are a kind of biomedical materials with light weight, multi-function and good biological safety. If they are used as special protective coating on the surface of degradable magnesium alloys and deal well with the biological function and mechanical compatibility of surfaces between them, it will be important direction to develop advanced magnesium alloys materials and their applications. In this paper, the latest research progress of biodegradable natural and synthetic polymer coatings on magnesium based alloys is reviewed, and the development trend of its research and development and application in the future is put forward.

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馮名城,李衛(wèi),符青云,于振濤.鎂合金表面可降解聚合物改性涂層研發(fā)及應(yīng)用[J].稀有金屬材料與工程,2021,50(9):3366~3374.[Feng Mingcheng, Li Wei, Fu Qingyun, Yu Zhentao. Development and application of degradable polymer modified coating on magnesium alloy surface[J]. Rare Metal Materials and Engineering,2021,50(9):3366~3374.]
DOI:10.12442/j. issn.1002-185X.20200740

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  • 收稿日期:2020-09-22
  • 最后修改日期:2020-10-13
  • 錄用日期:2020-10-23
  • 在線發(fā)布日期: 2021-09-27
  • 出版日期: 2021-09-24