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國外生物醫(yī)用鈦合金的發(fā)展現(xiàn)狀
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Development and Application of Biomedical Ti Alloys Abroad
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    摘要:

    綜述了近年來國外在生物醫(yī)用鈦及鈦合金方面的研究與開發(fā)現(xiàn)狀。為了取代普遍使用的Ti-6Al-4V合金,研發(fā)了多種無毒無敏感性元素、低彈性模量、高力學(xué)性能的新型β型鈦合金;采用多孔技術(shù)并調(diào)節(jié)孔隙率,使材料的彈性模量與人體骨骼基本相當(dāng),通過將聚合物滲入到多孔鈦的方法彌補多孔鈦強度的降低,并使材料具有更好的生物相容性;為適應(yīng)矯形外科領(lǐng)域的需求,開發(fā)了多孔TiNi超彈性形狀記憶合金,從而克服了骨與植入體之間結(jié)合力弱以及彈性模量不匹配的弊端。此外,研發(fā)了多種不含毒性和過敏性元素的β型超彈性形狀記憶鈦合金,可以替代TiNi合金而更安全地應(yīng)用于醫(yī)學(xué)領(lǐng)域;開發(fā)了多種鈦的表面改性技術(shù),通過改性層的沉積及表面硬化使植入體的生物相容性和抗磨損性得到提高。

    Abstract:

    Research and development of titanium and titanium alloys for biomedical applications abroad during last years were reviewed. Several kinds of low Young’s modulus, high mechanical properties, nontoxic and allergy-free b-type titanium alloys were developed to replace the widely used Ti-6Al-4V alloy. In order to reduce the Young’s modulus of the metals to a level similar to that of cortical bone, it is very effective to make titanium and its alloys porous and to adjust their porosity. The decrease in the strength of porous titanium can be significantly inhibited by penetrating polymer into the porous titanium through pressing, by which the biocompatibility can also be further improved. In order to meet the requirements in orthopaedic surgery field, porous TiNi superelastic shape memory alloy has been developed to overcome the drawbacks like weak interfacial bonds and mismatch of Young’s modulus between bone and implants. In addition, several kinds of nontoxic and allergy-free b-type superelastic shape memory titanium alloys were developed to substitute TiNi alloy with the aim to assure a more safety use in medical field. A tremendous number of surface modification techniques related to the deposition of modified surface layer and surface hardening were developed to improve the biocompatibility and wear resistance of titanium implants.

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朱康平,祝建雯,曲恒磊.國外生物醫(yī)用鈦合金的發(fā)展現(xiàn)狀[J].稀有金屬材料與工程,2012,41(11):2058~2063.[Zhu Kangping, Zhu Jianwen, Qu Henglei. Development and Application of Biomedical Ti Alloys Abroad[J]. Rare Metal Materials and Engineering,2012,41(11):2058~2063.]
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  • 收稿日期:2012-01-11
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