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多孔β型鈦合金及其微弧氧化涂層的體內(nèi)植入研究
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國家自然科學(xué)基金（面上項(xiàng)目）(30870611)


Implantation Study of Porous β Titanium Alloy and Its MAO Coatings
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    摘要:

    采用球形TLM:Ti-Zr-Sn-Mo-Nb粉末松裝燒結(jié)在中心件表面制備多孔件，利用微弧氧化技術(shù)在多孔件表面進(jìn)行改性，并制備復(fù)合有BMP的涂層。對(duì)多孔件和微弧氧化件的表面形貌、結(jié)構(gòu)和成分進(jìn)行分析；通過動(dòng)物體內(nèi)植入實(shí)驗(yàn)評(píng)價(jià)β型鈦合金多孔材料生物涂層周圍骨組織界面的新骨形成情況。結(jié)果表明：3種表面涂層均具有良好的生物相容性，但PCI/HA和PCI/HA 2種復(fù)合涂層組較PCI組有明顯的骨誘導(dǎo)活性，具有良好的臨床應(yīng)用前景。

    Abstract:

    Porous pieces were prepared with the alloy powder (TLM:Ti-Zr-Sn-Mo-Nb) and centre stick by means of sintering. The surface of porous pieces was modified with MAO. Another composite coating with BMP was prepared. The surface morphology, microstructure and composition of the three kinds of test pieces were analyzed. The new bone tissue around the coatings of these test pieces were evaluated according to animal implantation experiment. The results show that all of the three surface coatings have good biocompatibility. The PCI/HA group and PCI/HA/BMP group have excellent osteoconductivity and a good prospect of clinical application.

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井文森,韓建業(yè),張明華,蔡和平,于振濤,高銅拴.多孔β型鈦合金及其微弧氧化涂層的體內(nèi)植入研究[J].稀有金屬材料與工程,2012,41(9):1657~1660.[Jing Wensen, Han Jianye, Zhang Minghua, Cai Heping, Yu Zhentao, Gao Tongshuan. Implantation Study of Porous β Titanium Alloy and Its MAO Coatings[J]. Rare Metal Materials and Engineering,2012,41(9):1657~1660.]
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  • 收稿日期:2011-09-18
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