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2種牙科貴金屬鑄造合金的細(xì)胞毒性研究
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TG146.3

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Cytotoxicity of Two Kinds of Casting Alloys of Dental Precious Metals
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    摘要:

    采用四甲基偶氮唑鹽微量酶反應(yīng)比色法(MTT法)對(duì)自行研制的2種Au-Ag-Pd-Cu牙科鑄造合金的細(xì)胞毒性進(jìn)行了研究。并用相差顯微鏡對(duì)細(xì)胞形態(tài)進(jìn)行了觀察分析。試驗(yàn)使用的細(xì)胞株為小鼠結(jié)締組織成纖維細(xì)胞(L-929)，培養(yǎng)液為含5％小牛血清(FBS)的RPMI1640。結(jié)果表明：細(xì)胞在2種Au-Ag-Pd-Cu牙科鑄造合金的浸漬液中培養(yǎng)3d和5d后，細(xì)胞形態(tài)良好，生長(zhǎng)旺盛；2種合金的細(xì)胞毒性級(jí)別為0—1級(jí)，具有良好的細(xì)胞相容性。

    Abstract:

    The biocompatibility of two dental casting alloys of Au-Ag-Pd-Cu was investigated by MTT assay. The cells morphology was observed with a phase-contrast microscope. In the experiment, the L-929 cell line and RPMI1640 with 5% FBS were used. The results show that the cell morphology is good, and the growth of cells is vigorous after the cells have been cultured and steeped in the two alloys for 3 days and 5 days. The cytotoxicity of two alloys was ranked as 0 ~ 1 with a good biocompatibility.

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趙西成 蘭新哲 尚再燕 丁弘仁.2種牙科貴金屬鑄造合金的細(xì)胞毒性研究[J].稀有金屬材料與工程,2003,(10):822~824.[Zhao Xicheng, Lan Xinzhe, Shang Zaiyan, Ding Hongren. Cytotoxicity of Two Kinds of Casting Alloys of Dental Precious Metals[J]. Rare Metal Materials and Engineering,2003,(10):822~824.]
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  • 最后修改日期:2002-09-15
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