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新型微弧氧化鈦基種植材料的細(xì)胞毒性研究
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Q959.133

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湖北省科技攻關(guān)項(xiàng)目(4-260)


The Cytotoxicity Study of Novel Implant Material Modified by Microarc Oxidation
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    摘要:

    采用四甲基偶氮唑鹽微量酶反應(yīng)比色法(MTT法)對微弧氧化處理的鈦基種植材料的細(xì)胞毒性進(jìn)行研究,并用相差顯微鏡對細(xì)胞形態(tài)進(jìn)行了觀察與分析。本研究采用原代培養(yǎng)鑒定后的成骨細(xì)胞,與不同材料三維培養(yǎng),進(jìn)行種植體材料的細(xì)胞毒性研究。結(jié)果表明:微弧氧化處理的材料表面細(xì)胞形態(tài)良好,生長旺盛,細(xì)胞計(jì)數(shù)及MTT測定結(jié)果與其它組比較,具有顯著性差異,細(xì)胞毒性級別優(yōu)于0級,具有良好的細(xì)胞相容性。

    Abstract:

    Cytotoxicity of novel implant material modified by microarc oxidation technique has been investigated in this study. The cells configulation was observed on different surfaces evaluated for 2 d, 4 d and 6 d. The results showed that the cell attachment, morphology and proliferation were influenced by the different surface treatments, and a significant increase of the osteoblast cell activity was observed on the porous MAO-Ti coating. Based on these results, it was suggested that the porous MAO-Ti surface has a better biocompatibility and an excellent electrochemical performance than pure titanium surface treatments.

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楊成 孟麗娥 田元 黃韜.新型微弧氧化鈦基種植材料的細(xì)胞毒性研究[J].鈦工業(yè)進(jìn)展,2007,24(1):25-28.

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  • 最后修改日期:2006-08-08
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